PAX6-dependent epithelial differentiation and developmental trajectories of the ocular surface are elucidated through single-cell RNA sequencing of hiPSC-derived ocular organoids. This study provides ...

The increasing production and environmental dissemination of synthetic chemicals, including pharmaceuticals and emerging contaminants, raise important ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

Antibody drugs such as monoclonal antibodies (mAb), bispecific antibodies, antibody-drug conjugates (ADCs), and nanobodies garnered increased interest in research and development circles. Sino ...

A court decision in a wrongful-death case in Alabama last month drew a spotlight to in vitro fertilization, an increasingly popular method of conceiving babies for the infertile. In vitro — Latin for ...

This Research Topic will showcase advances in non-animal toxicology that improve the mechanistic understanding and predictive assessment of chemical safety.

For example, the hemoglobin denaturation (HD) test and the Ocular Irritection test are in chemico alternatives to the Draize rabbit test. The Draize rabbit test was developed in 1944 to test cosmetic ...

It may soon be possible to coax human skin cells into becoming functional eggs and sperm using a technique known as “in vitro gametogenesis”. This involves the creation (genesis) of eggs and sperm ...

Don't miss the Official Trailer for In Vitro, a sci-fi thriller distributed by Saban Films. Layla lives on a remote cattle farm with her husband Jack, a biotech researcher who’s developed a new ...

Providers in Alabama are resuming some in vitro fertilization services Thursday, the day after the state’s Republican governor signed a bill into law aimed at protecting IVF patients and providers ...