Dynamic switching between revival stem cells and conventional intestinal stem cells enables efficient tissue repair without ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

Cedars-Sinai Health Sciences University investigators have for the first time created human intestinal organoids that include ...

Drosophila melanogaster has long served as a powerful model for dissecting the principles of tissue homeostasis and regeneration. Within the adult midgut, intestinal stem cells (ISCs) perform the ...

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection ...

An international study led by Paolo Fiorina from Boston Children’s Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Now, scientists have discovered a new role: shaping stem cells, which in turn regulate development. In a study published in Cell Stem Cell, researchers found that metabolites produced by the mother’s ...

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...

Colorectal cancers, which kill more than 900,000 people each year, are notoriously heterogeneous. The cell type and the genetic mutations that give rise to the tumors and the effect of the tumor ...

If we could listen to stem cells closely enough, we might hear them whisper, “mechanosenses tingling.” After all, stem cells sense and react to the physical forces around them, maintaining their ...